Scientific articles

Oxygen-Ozone Therapy for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials

Cristiano Sconza 1 , Stefano Respizzi 1 , Lorenzo Virelli 1 , Filippo Vandenbulcke 2 , Francesco Iacono 3 , Elizaveta Kon 4 , Berardo Di Matteo 3 1 Department of Rehabilitation and Functional Recovery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy. 2 Department of Biomedical Sciences, Humanitas University, Rozzano,...

24 September 2020
Scientific articles , World news

Oxygen-Ozone as Adjuvant Treatment in Early Control of COVID-19 Progression and Modulation of the Gut Microbial Flora (PROBIOZOVID)

Brief Summary: Italy was the first European country affected by a severe outbreak of the Severe Acute Respiratory Syndrome – CoronaVirus-2 (SARS-CoV-2) epidemic emerged from Wuhan region (China), with a high morbidity and mortality associated with the disease. In light of its pandemic spread and the very limited therapeutic options,...

30 April 2020
Scientific articles

Molecular mechanisms in cognitive frailty: potential therapeutic targets for oxygen-ozone treatment

Catia Scassellatia Miriam Ciani Antonio Carlo Galoforo Roberta Zanardini Cristian Bonvicini Cristina Geroldi Abstract In the last decade, cognitive frailty has gained great attention from the scientific community. It is characterized by high inflammation and oxidant state, endocrine and metabolic alterations, mitochondria dysfunctions and slowdown in regenerative processes and immune...

21 February 2020
Scientific articles

Modulation of Oxidative Stress by Ozone Therapy in the Prevention and Treatment of Chemotherapy-Induced Toxicity: Review and Prospects

Bernardino Clavo Francisco Rodríguez-Esparragón Delvys Rodríguez-Abreu Gregorio Martínez-Sánchez Pedro Llontop David Aguiar-Bujanda Leandro Fernández-Pérez Norberto Santana-Rodríguez Abstract Background: Cancer is one of the leading causes of mortality worldwide. Radiotherapy and chemotherapy attempt to kill tumor cells by different mechanisms mediated by an intracellular increase of free radicals. However, free radicals...

20 January 2020