Scientific articles

Molecular mechanisms in cognitive frailty: potential therapeutic targets for oxygen-ozone treatment

Catia Scassellatia Miriam Ciani Antonio Carlo Galoforo Roberta Zanardini Cristian Bonvicini Cristina Geroldi Abstract In the last decade, cognitive frailty has gained great attention from the scientific community. It is characterized by high inflammation and oxidant state, endocrine and metabolic alterations, mitochondria dysfunctions and slowdown in regenerative processes and immune...

21 February 2020
Scientific articles

Modulation of Oxidative Stress by Ozone Therapy in the Prevention and Treatment of Chemotherapy-Induced Toxicity: Review and Prospects

Bernardino Clavo Francisco Rodríguez-Esparragón Delvys Rodríguez-Abreu Gregorio Martínez-Sánchez Pedro Llontop David Aguiar-Bujanda Leandro Fernández-Pérez Norberto Santana-Rodríguez Abstract Background: Cancer is one of the leading causes of mortality worldwide. Radiotherapy and chemotherapy attempt to kill tumor cells by different mechanisms mediated by an intracellular increase of free radicals. However, free radicals...

20 January 2020
Scientific articles , World news

Low back pain related to a sacral insufficiency fracture: role of paravertebral oxygen-ozone therapy in a paradigmatic case of nociplastic pain.

Author: De Sire A, Baricich A, Minetto MA, Cisari C, Invernizzi M. Abstract We describe the case of a 68-year-old woman with an acute episode of severe low back pain (LBP) resistant to opioids, who had experienced a sacral insufficiency fracture (SIF) two years earlier. At clinical examination, patient reported...

30 September 2019
Scientific articles , World news

Treatment of Osteoradionecrosis of the Jaw with Ozone in the Form of Oil-based Gel: 1-year follow-up.

Author Bianco E1, Maddalone M2, Porcaro G3, Amosso E3, Baldoni M3. Author information 1) Department of Surgery and Translational Medicine, University of Milano Bicocca, Monza, Italy. 2) Department of Orthodontics, University of Milano Bicocca, Monza, Italy. 3) Department of Surgery and Translational Medicine, University of Milano Bicocca, Monza, Italy. Abstract...

4 September 2019